Immunology (IMM)

IMM 5100  Basic Graduate Immunology  (3 Credits)  
H. Borges da Silva (Fall) – Structure, genetics, and function of immunoglobulins; biosynthesis of antibody; cellular regulation of immune response; tumor and transplantation immunology; immune response to infectious agents; autoimmunity and immune deficiencies. Course previously listed as CORE 6200.
Grading: Standard Letter  
IMM 5200  Introduction to Flow Cytometry  (1 Credit)  
V. Shapiro (Summer) – This course will teach the basics of flow cytometry, including how a cytometer functions, designing a panel compensation, statistics, analysis, and interpretation. New technology including new fluorochromes and mass cytometry (CyTOF) are also discussed. No prerequisites are required. The course consists of 10 hours of lecture from RST videoconferenced to AZ and FL, plus 4 hours of hands-in/demonstration plus a virtual demonstration/analysis.
Grading: Sat / Unsat  
IMM 6862  Current Topics in Cell Activation and Signaling  (1 Credit)  
D. Billadeau, V. Shapiro (Winter, Summer) – Weekly discussions of recent scientific literature on topics related to receptors, transmembrane signaling mechanisms, and gene expression. IMM degree candidates are given preference for this course.
Grading: Sat / Unsat  
IMM 6863  Current Topics in Immunology  (1 Credit)  
F. Lucien-Matteoni (Fall, Spring) – Current literature on important areas of immunology. Critical review of methods, results and findings. Register in the quarter you present (1 cr./yr.). Attendance required fall and spring. IMM degree candidates are given preference for this course.
Grading: Sat / Unsat  
IMM 6865  Regenerative T Cell Immunotherapy and Cellular Engineering  (3 Credits)  
S. Kenderian (Spring) – This course is a week-long instructional class involving internal and external guest speakers from multiple different fields in cancer immunotherapy. It covers commonly used and studied cancer immunotherapy tools, including cell therapy, nucleic acid-based cancer vaccines, therapeutic monoclonal antibodies, etc. Students will be exposed to the latest ongoing research in cancer immunotherapy and will have opportunities to discuss unsolved challenges and potential solutions in the fields with the invited scientists. Students will be designing and presenting their own final projects as small groups and will be graded by course director and teaching assistant. By the end of the course, students are expected to understand common platforms of cancer immunotherapies and corresponding advantages and disadvantages. *This class will be offered Spring 2024*
Grading: Sat / Unsat  
IMM 6867  Current Topics in Barrier Immunology  (1 Credit)  
K. Knoop (Winter, Spring) – This journal club discusses recent work on the broad area of clinical and translational immunology occurring on barrier surfaces: skin, gastrointestinal tract, urogenital track, and respiratory track. Topics will include hypersensitivity responses, microbial influences on immunity, mucosal immunology, and mechanisms and treatment of immune-mediated diseases affecting barrier surfaces. Diseases on interest include allergic disorders, inflammatory bowel diseases, and urogenital infections.
Prerequisites: (IMM 5100 or CORE 6200)  
Grading: Standard Letter  
IMM 6878  Tutorial in Innate Immunity  (2 Credits)  
S. Oh, A. Ting (Odd: Winter) – Course is designed to provide an in-depth understanding of the role of innate immunity in health and disease. The final grade will be based on class participation and the grade achieved on the comprehensive final exam. Prerequisite is successful completion of IMM 5100 or Mayo Medical School, Block V, Normal Function. A non-degree candidate may enroll with the contingency of having completed IMM 5100 with a grade of B or better and receiving permission from the Immunology Graduate Program Director and individual tutorial course directors. No auditing allowed for non-degree candidates.
Prerequisites: (IMM 5100  
Grading: Standard Letter  
IMM 6879  Tutorial in Adaptive Immunity  (2 Credits)  
K. Hirohito, L. Rogers (Even: Spring) – Course is designed to provide an in-depth understanding of adaptive immunity in health and disease. Prerequisites for this course are successful completion of Immunology IMM 5100 or Mayo Medical School, Block V, Normal Function. Offered in first half of spring quarter during even years only.
Prerequisites: (IMM 5100 or CORE 6200)  
Grading: Standard Letter  
IMM 6880  Tutorial in Tissue Immunity  (2 Credits)  
A. Johnson, K. Knoop (Odd: Spring) – Course is designed to provide an in-depth understanding of the how the the immune system communicates and works in the body tissues in health and disease. The final grade will be based on class participation and the grade achieved on the comprehensive final exam. Prerequisites for this course are successful completion of Immunology IMM 5100 or Mayo Medical School, Block V, Normal Function. A non-degree candidate may enroll with the contingency of having completed IMM 5100 with a grade of B or better and receiving permission from the Immunology Graduate Program Director and individual tutorial course directors. No auditing allowed for non-degree candidates.
Prerequisites: (IMM 5100 or FNDN 7151)  
Grading: Standard Letter  
IMM 6882  Tutorial in Bridging Innate and Adaptive Immunity  (2 Credits)  
M. Curtis, W.K. Ip (Odd: Winter) – Course is designed to provide an in-depth understanding of the how the innate and adaptive components of the immune system communicate in health and disease. The final grade will be based on class participation and the grade achieved on the comprehensive final exam. Prerequisites for this course are successful completion of Immunology IMM 5100 or Mayo Medical School, FNDN 7151 Immunology. A non-degree candidate may enroll with the contingency of having completed IMM 5100 with a grade of B or better and receiving permission from the Immunology Graduate Program Director and individual tutorial course directors. No auditing allowed for non-degree candidates. Offered in second half of winter quarter during odd years only.
Prerequisites: (IMM 5100 or FNDN 7151)  
Grading: Standard Letter  
IMM 6884  Tutorial in Generation and Function of T Cells  (2 Credits)  
F. Gounari, V. Shapiro (Even: Winter) – The course is designed to provide an in-depth understanding of the generation and function of T lymphocytes in health and disease. The final grade will be based on class participation and the grade achieved on the comprehensive final exam. Prerequisites for this course are successful completion of Immunology IMM 5100 or Mayo Medical School, Block V, Normal Function. Offered in second half of winter quarter during even years only.
Prerequisites: (IMM 5100 or CORE 6200)  
Grading: Standard Letter  
IMM 6885  Tutorial in Generation and Function of B Cells  (2 Credits)  
K. Medina, A. Novak (Even: Winter) – This course is designed to provide an in depth understanding of the generation and function of B lymphocytes in health and disease. The final grade will be based on class participation and the grade achieved on the comprehensive final exam. The prerequisites are successful completion of Immunology IMM 5100 or Mayo Medical School, Block V, Normal Function, Immunology course. Offered in first half of winter quarter during even years only.
Prerequisites: (IMM 5100 or CORE 6200)  
Grading: Standard Letter